Izabal is a very important department, with hosts the only Caribbean coast of Guatemala. The cruise destination Puerto Santo Tomás de Castilla is here, and is one of the most important sea ports of the country.

The most famous places are:

• Puerto Barrios (a coast town)
• Livingston
• Quriguá (Mayan ruins famous for its monoliths)
• San Felipe Castle (a colonial fort)
• Rio Dulce (A navegable river)
• Lago de Izabal (the biggest lake of the country)
• Punta de Manabique